Do Dried Blood Spots (DBS) Have the Potential to Support Result Management Processes in Routine Sports Drug Testing?

Do Dried Blood Spots (DBS) Have the Potential to Support Result Management Processes in Routine Sports Drug Testing? / Mario Thevis, Tiia Kuuranne, Josef Dib, Andreas Thomas, Hans Geyer. - (Drug Testing and Analysis (2020, 16 March); p. 1-12).
- PMID: 32180361.
- DOI: 10.1002/dta.2790
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Abstract

Dried blood spots (DBS) have been considered as complementary matrix in sports drug testing for many years. Especially concerning substances prohibited in-competition only, the added value of DBS collected concomitantly with routine doping control urine samples has been debated, and an increasing potential of DBS has been discussed in the scientific literature. To which extent and under which prerequisites DBS can contribute to enhanced anti-doping efforts is currently evaluated. As a proof-of-principle, two analytical applications, one targeting cocaine/benzoyl ecgonine and the other prednisone/prednisolone, are presented in this perspective to indicate potential added value but also presently existing limitations of the DBS approach.

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Science
Study
Date:
16 March 2020
People
Dib, Josef
Geyer, Hans
Kuuranne, Tiia
Thevis, Mario
Thomas, Andreas
Country
Germany
Switzerland
Language
English
Other organisations
Deutsche Sporthochschule Köln (DSHS) - German Sport University Cologne
European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)
Laboratories
Lausanne, Switzerland: Laboratoire Suisse d’Analyse du Dopage
Analytical aspects
Blood testing method
Testing method development
Doping classes
S6. Stimulants
S9. Glucocorticosteroids
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Cocaine
Prednisolone
Prednisone
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