Evolution of serum lipids in two male bodybuilders using anabolic steroids

Evolution of serum lipids in two male bodybuilders using anabolic steroids / Francisco Lajarin, Rogelio Zaragozá, Isabel Tovar, Pedro Martinez-Hernandez. - (Clinical Chemistry 42 (1996) 6 (June); p. 970-972).
- PMID: 8665691
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Abstract

We followed weekly the evolution of serum lipid concentrations in two bodybuilders undergoing a cycle of treatment with anabolic steroids. These drugs caused maximum depression of high-density lipoprotein cholesterol concentrations by 69.1% in the fifth week after the beginning of the cycle for subject 1, and by 72.4% in the fourth week for subject 2. Maximum increases in low-density lipoprotein cholesterol concentrations were 144% and 156%, respectively. Total cholesterol and apolipoprotein (apo) B were highly increased with anabolic steroid use. We also saw depression of apo A-I by 84% and 91%, and lipoprotein(a) decreased to undetectable amounts in both cases. These effects were reversed 10 weeks after the end of the steroid cycle in subject 1, but subject 2 still presented abnormal concentrations of serum lipids 13 weeks after drug cessation. The periods until reversibility of anabolic steroid effects on lipids were longer than those reported in previous studies.

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Science
Case report
Date
12 February 1996
People
Lajarin, Francisco
Martinez-Hernandez, Pedro
Tovar, Isabel
Zaragozá, Rogelio
Country
Spain
Language
English
Sport/IFs
Bodybuilding & Fitness (IFBB) - International Federation of Bodybuilding & Fitness
Other organisations
Hospital Clínico Universitario Virgen de la Arrixaca
Doping classes
S1. Anabolic Agents
Medical terms
Cardiovascular diseases
Health effects
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Scientific article
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Date generated
18 May 2020
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21 May 2020
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