Anabolic Steroid-induced Mania

Anabolic Steroid-induced Mania / Daniel G. Franey, Eduardo D. Espiridion. - (Cureus 10 (2018) 8 (August 20)

  • PMID: 30357054
  • PMCID: PMC6197512
  • DOI: 10.7759/cureus.3163


There are numerous reports of the psychiatric effects of anabolic-androgenic steroid (AAS) use. However, these effects have not been clearly elicited in controlled clinical trials. This discrepancy is largely due to the presence of a variety of synergistic factors seen in the real-life setting of AAS abuse. In this case, we report a patient in acute mania admitted to Frederick Memorial Hospital in Frederick, Maryland. He had no prior history or family history of manic episodes. His symptoms were refractory to initial pharmacologic intervention. The onset of his symptoms was likely related to the initiation of AAS use. However, his symptoms were likely potentiated by heavy daily cannabis use. The patient showed a gradual improvement over the second week of his hospitalization. He was discharged on antipsychotics and scheduled to follow up with a therapist and psychiatrist.

Original document


Case report
20 August 2018
Espiridion, Eduardo D.
Franey, Daniel G.
United States of America
Other organisations
Frederick Health Hospital
West Virginia School of Osteopathic Medicine (WVSOM)
West Virginia University (WVU)
Doping classes
S1. Anabolic Agents
S8. Cannabinoids
Medical terms
Health effects
Psychiatric disorders
Document category
Scientific article
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Pdf file
Date generated
4 May 2021
Date of last modification
2 December 2021
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