Anabolic steroids and extreme violence: a case of murder after chronic intake and under acute influence of metandienone and trenbolone

Anabolic steroids and extreme violence: a case of murder after chronic intake and under acute influence of metandienone and trenbolone / Frédéric Aknouche, Laurie Gheddar, Angeline Kernalléguen, Christophe Maruejouls, Pascal Kintz

  • International Journal of Legal Medicine 135 (2021) 4; p. 1449-1453
  • PMID: 33813613
  • DOI: 10.1007/s00414-021-02587-y


Abstract

A 32-year-old male went to the police to claim he just killed his girlfriend by inflicting several stabs with a kitchen knife. He was very nervous and particularly aggressive. About 90 min after the assault, a blood specimen was collected with natrium fluoride as preservative. The blood was free of alcohol, pharmaceuticals and drugs of abuse, but tested positive by LC-MS/MS for metandienone (32 ng/mL) and trenbolone (9 ng/mL). The perpetrator admitted regular consumption of anabolic steroids to enhance his muscular mass, as he was a professional security agent. To document long-term steroid abuse, a hair specimen was collected 3 weeks after the assault, which tested positive for both drugs. Segmental analyses revealed in the proximal 1.5 cm segment, corresponding to the period of the assault, the simultaneous presence of metandienone (11 pg/mg) and trenbolone (14 pg/mg), while only metandienone (3 pg/mg) was identified in the distal 1.5 cm segment. As aggressiveness and violence can be associated with abuse of anabolic steroids, the aetiology of this domestic crime was listed to be due impulsive behaviour in a context of antisocial lifestyle.

Parameters

Science
Case report
Date
4 April 2021
People
Aknouche, Frédéric
Gheddar, Laurie
Kernalléguen, Angeline
Kintz, Pascal
Maruejouls, Christophe
Country
France
Language
English
Legal Terms
Criminal case / judicial inquiry
Other organisations
Institut de médecine légale de Strasbourg
Analytical aspects
Mass spectrometry analysis
Doping classes
S1. Anabolic Agents
Substances
Metandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3-one)
Trenbolone (17β-hydroxyestr-4,9,11-trien-3-one)
Medical terms
Violent behavior
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Date generated
8 December 2021
Date of last modification
13 December 2021
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