In July 2018 the United World Wrestling (UWW) has reported an anti-doping rule violation against the minor Athlete Dmitrii Elkanov after his sample tested positive for the prohibited substance Dehydrochlormethyltestosterone.

After notification a provisional suspension was ordered and the Athlete filed a statement in his defence. The UWW Anti-Doping Panel settled this case based on the written submissions of the parties.

The wrestler stated that he used a supplement called “Ecdysterone Ace” in 2017 for four weeks. He explained how he searched for information on the internet and how and where he bought the supplement.

The Panel holds that the substance found in the sample provided by the athlete was a metabolite of Dehydrochlormethyltestosterone (Turinabol). However, according to a study on the excretion of ecdysterone in human urine, ecdysterone does not seem to produce turinabol as a metabolite, but two other different metabolites. The Panel concludes that the Athlete failed to establish how the substance entered his system.

Therefore the UWW Anti-doping panel decides on 20 August 2018 that the wrestler, Mr Dmitrii Elkanov:

I.) Is found to have committed an anti-doping rules violation, namely article 2.1 of the Rules;
II.) Is imposed a period of ineligibility of four (4) years, starting from 28 July 2018 until 27 July 2022 included.
III.) The results obtained in the World Championship Cadet are disqualified. With this disqualification, the ranking must be modified accordingly, and the place earned for the Youth Olympic Games 2018 is to be reallocated in accordance with the 2018 qualifying system for Wrestling.
IV.) The Russian Wrestling Federation is imposed a fine of 20’000 Swiss Francs.

In September 2017 the Disciplinary Commission of the Olympic Council of Asia (OCA) decided to disqualify the results of the Turkmen wrestler Gulnar Hayytvavyeva after her sample tested positive for the prohibited substances 4-Methylhexan-2-amine (methylhexaneamine, 1,3-dimethylamylamine, 1,3 DMAA) and 4-Methylpentan-2-amine (1,3-dimethylbutylamine).

Here the Athlete stated that she only used prescribed medication and supplement drinks which didn’t contain prohibited substances.

Hereafter the case was transferred to United World Wrestling (UWW) and proceedings were opened in June 2018 against the Athlete. After notification a provisional suspension was ordered and the Athlete failed to respond to any of the communications from UWW.

Without the Athlete’s response the UWW Anti-Doping Panel finds that the Athlete committed an anti-doping rule violation and that she failed to explain how the substance entered her system without grounds for a reduced sanction.

Therefore the UWW Anti-Doping Panel decides on 7 November 2018 that the wrestler, Ms Gulnar Hayytvavyeva:

I.) Is found to have committed an anti-doping rules violation, namely article 2.1 of the Rules;
II.) Is imposed a period of ineligibility of two (2) years, from the date of decision, until 6 November 2020 included.

In July 2018 United World Wrestling (UWW) has reported an anti-doping rule violation against the Iraqi wrestler Husham Majeed Ali Al Thaalebi after his sample tested positive for the prohibited substance Testosterone. After notification a provisional suspension was ordered and the Athlete filed a statement in his defence.

In his submission the Athlete explained with evidence that he underwent treatment with Testosterone for his infertility. However the UWW Anti-Doping Panel deems that the filed medical evidence was questionable and when requested hereafter the Athlete didn't produce any supporting official documents and credible testimonies about his treatment. Further the Doha Lab reported that the concentration found in the Athlete’s sample didn’t support the allegation of treatment for infertility. As a result the Panel concludes that the Athlete failed to prove, on a balance of probability, how the prohibited substance entered his system.

Therefore the UWW Anti-Doping Paneld decides on 28 January 2019 to impose a 4 year period of ineligibility on the Athlete starting on 28 July 2018. Further the Panel decides to impose a CHF 20’000 fine on the Iraq Wresting Federation.

In August 2018 the United World Wrestling (UWW) has reported an anti-doping rule violation against the Kyrgyzian wrestler Muslim Evloev after his sample tested positive for the prohibited substance Dehydrochlormethyltestosterone (Turinabol). After notification a provisional suspension was ordered and the Athlete filed a statement with evidence in his defence.

In his submission the Athlete denied the intentional use of the substance and with statements of his coach and his teamdoctor he raised the assumption that the positive test result was caused by the ingestion of contaminated meat. Also the Athlete sent samples of his medication and supplements for analysis to the Cologne Lab.

After consultation of WADA and the Laboratory the UWW Anti-Doping Panel rejected the Athlete’s assumption about the meat or dairy contamination with Turinabol and failed to produce evidence in support of his assumption. Also the Panel holds that the Athlete didn’t file any test results of the Cologne Lab regarding analysis of his medication and supplements he used. As a result the Panel concludes that the Athlete failed to establish how the substance entered his system.

Therefore the UWW Anti-Doping Panel decides on 2 May 2019 to impose a 4 year period of ineligibility on the Athlete starting on the date of the provisional suspension, i.e. on 15 August 2018. Further the Panel decides to impose a CHF 20’000 fine on the Kyrgyz Wresting Federation.

In September 2017 the Disciplinary Commission of the Olympic Council of Asia (OCA) decided to disqualify the results of the Mongolian wrestler Orkhon Purevdorj after her A and B samples tested positive for the prohibited substance Stanozolol.

Hereafter the case was transferred to United World Wrestling (UWW) and proceedings were opened in September 2018 against the Athlete. After notification a provisional suspension was ordered. The Athlete filed a statement in her defence and she was heard for the UWW Anti-Doping Panel.

The Athlete accepted the test results and explained that an intravenous injection was administered to her and other wrestlers in July 2018 by her club’s doctor. She also raised the hypothesis that sabotage caused the positive test result.

The Panel established that the product in question administered through intravenous injection was made of soybean oil and lecithin and there was no indication on the label of the product that it contained any anabolic steroid. Neither produced the Athlete any evidence that this product had been contaminated.

The Panel holds that the intravenous injection was administered without medical necessity and it can be regarded as a prohibited method M2 in the prohibited list. Previously the Athlete’s accusation of sabotage was already investigated but it did not result in any charge for sabotage or any other violation.

The Panel finds that both theories raised by the Athlete are speculations and do not satisfy the degree of proof placed on her to establish how the substance entered her system nor grounds for a reduced sanction.

Therefore the UWW Anti-Doping Panel decides on 15 February 2019 to impose a 4 year period of ineligibility on the Athlete starting on the date of the provisional suspension, i.e. on 17 September 2018.
Further the Panel decides to impose a CHF 20’000 fine on the Mongolian Wresting Federation.

In September 2017 the Disciplinary Commission of the Olympic Council of Asia (OCA) decided to disqualify the results of the Turkmenian wrestler Rustem Nazarov after his sample tested positive for the prohibited substance Furosemide. Here the Athlete stated that he had used prescribed medication for his kidney condition and was unaware that this medication contained a prohibited substance.

Hereafter the case was transferred to United World Wrestling (UWW) and proceedings were opened in September 2018 against the Athlete. After notification a provisional suspension was ordered and the Athlete failed to respond to any of the communications from UWW.

Without the Athlete’s response and without any evidence in his defence the UWW Anti-Doping Panel finds that the Athlete committed an anti-doping rule violation and that he failed to explain how the substance entered his system without grounds for a reduced sanction.

Therefore the UWW Anti-Doping Panel decides on 20 November 2018 that the wrestler, Mr Rustem Nazarov:

1.) Is found to have committed an anti-doping rules violation, namely article 2.1 of the Rules;
2.) Is imposed a period of ineligibility of two (2) years, from the date of the provisional suspension, i.e. from 17 September 2018 until 16 September 2020 included.

Related case:
UWW 2018 UWW vs Aibek Usupov
July 23, 2018

On 3 March 2018, after his defeat in the 3-5 finals of the 2018 Asian Championships, the Kyrgyz Athlete Aibek Usupov was approached by a chaperone and notified for a doping control. The Athlete asked for a moment to calm down after his defeat in that match and did not sign the form. According to the chaperone, who stayed with him all the time after he asked for a moment, the Athlete’s brother Mr Saiakbai Usupov came and told the chaperone that his brother would not provide a sample. The chaperone explained to the Athlete and Mr Saiakbai Usupov what the consequences would be for refusing the test. Despite this warning, Mr Saikbai Usupov persuaded his brother not to pass the test and both the Athlete and Mr Usupov walked away without justification.

Consequently in March 2018 United World Wrestling (UWW) has reported an anti-doping rule violation against the Athlete Aibek Usopov for his refusal to provide a sample. Mr Saiakbai Usupov was charged for complicity due to his involvement in his brother refusal.

After notification a provisional suspension was ordered and Mr Usupov filed a statement in his defence. The UWW Anti-Doping Panel settled this case based on the written submissions of the parties.

As in his brother’s statement of defence, Mr Usupov asserts that there was a confusion between him and his brother’s friend called Ulanbek Osmanaliev. However, the Panel holds that he did not bring any evidence forward to support this allegation nor a statement from Mr Osmanaliev himself which could have exonerated him.

The Panel accepts the detailed reports made by the Doping Control Officers (DCOs) and establish that Mr Usopov actively, aggressively and intentionally encouraged and persuaded his brother to refuse the doping control.

The panel is comfortably satisfied that all elements constituting a violation for complicity are present in this case: Mr Usupov’s physical and psychological conduct falls in the definition of Complicity which covers any intentional conduct which assists another to commit an anti-doping rule violation and meet the standard of proof required by UWW to establish the anti-doping rules violation.

Therefore the UWW Anti-doping panel decides on 24 July 2018 that the wrestler, Mr Saiakbai Usupov:
I.) Is found to have committed an anti-doping rules violation, namely article 2.9 of the Rules;
II.) Is imposed a period of ineligibility of two (2) years, starting from 28 March 2018 until 28 March 2020 included.

In May 2017 the United World Wrestling (UWW) has reported an anti-doping rule violation against the Iranian wrestler Seyed Mostafa S. Salehizadeh after his A and B samples tested positive for the prohibited substance Stanozolol. After notification a provisional suspension was ordered. The Athlete filed a statement in his defence and he was heard for the UWW Anti-Doping Panel.

The Athlete denied the intentional use of the substance and asserted that contaminated supplements caused the positive test. He also raised the hypothesis that an opponent might have sabotaged him during a training camp.

The Panel did not accept the Athlete's assertions and finds that he failed to establish how the prohibited substance entered his system nor producted evidence that supported the possible sabotage by an opponent.

Therefore the UWW Anti-Doping Panel decides on 28 January 2019 to impose a 4 year period of ineligibility on the Athlete starting on the date of the provisional suspension, i.e. on 7 May 2018. Further the Panel decides to impose a CHF 20’000 fine on the Iranian Wresting Federation.

National Anti-Doping Agency of Uzbekistan for 2021 activity reporting information / National Anti-Doping Agency of Uzbekistan (UzNADA). - Toshkent : Ўзбекистон Республикаси Вазирлар Маҳкамаси Ҳузуридаги Миллий Антидопинг Агентлиги, 2022

Validation of a GC/MS method for the detection
of two quinolinone-derived selective androgen receptor
modulators in doping control analysis / E. Gerace, A. Salomone, F. Fasano, Régis Afonso Costa, D. Boschi, A. Di Stilo, Marco Vincenti. - (Analytical and bioanalytical chemistry (2011) 400; p. 137–144)

• PMID: 21165606
• DOI: 10.1007/s00216-010-4569-8

Abstract

Selective androgen receptor modulators (SARMs) represent an emerging class of drugs likely to be abused in sport. For clinical applications, these substances provide a promising alternative to testosterone-replacement therapies and their advantages include oral bioavailability, androgen receptor specificity, tissue selectivity, and the absence of steroid-related side effects. Although not yet commercially available, since January 2008 SARMs have been included on the prohibited list issued yearly by the World Anti-Doping Agency (WADA), so control laboratories need to update their procedures to detect either the parent drugs or their metabolites. Within this context, two quinolinone SARM models were synthesized and automatically characterized to update the existing routine screening procedures. The conditions for the new target analytes are compatible with the existing laboratory protocols used for both in-competition and out-of-competition controls and can be included in them. Validation parameters according to ISO 17025 and WADA guidelines were successfully determined. For analytical determinations, spiked urine samples were hydrolyzed and extracted at pH 9.6 with 10 mL of tert-butyl methyl ether. Then, the analytes were subsequently converted into trimethylsilyl derivatives and detected by gas chromatography-mass spectrometry. The absence of interferents, together with excellent repeatability of both retention times and the relative abundances of diagnostic ions, allowed proper identification of all SARM analytes. The analytes' quantification was linear up to 500 ng/mL and precision criteria were satisfied (coefficient of variation less than 25% at 10 ng/mL). The limits of detection were 1 ng/mL for both SARMs, whereas recovery values were between 95.5 and 99.3%. The validated method can be efficiently used for urine screening of the 2-quinolinone-derived SARMs tested.