Improved Sprint Performance With Inhaled Long-Acting Β2-Agonists Combined With Resistance Exercise

Improved Sprint Performance With Inhaled Long-Acting Β2-Agonists Combined With Resistance Exercise / Michele Merlini, Greg Whyte, Sam Marcora, Mike Loosemore, Neil Chester, John Dickinson. - (International journal of sports physiology and performance (2019) 8 April ; p. 1-22).
- PMID: 30958069.
- DOI: 10.1123/ijspp.2018-0921


To investigate the impact of twice daily inhalation of 100 μg of salmeterol or 12 μg of formoterol in addition to a strength and power training programme over a 5-wk period on 30-m sprint, strength, power, mood, stress, and skinfold thickness.

In a randomized single-blind study, 23 male and 15 female nonasthmatic, recreationally active individuals were recruited (mean ± SD age 26.3 ± 5.4 y, weight 76.2 ± 11.5 kg, height 176.9 ± 8.5 cm). Participants completed 3 standardized whole-body strength and power training sessions per week for 5 wk. During the 5-wk training period they were assigned to a salmeterol (SAL), formoterol (FOR), or placebo (PLA) group. Participants used their inhaler twice per day as instructed and completed assessments of sprint, strength, and power at baseline and 1 wk after cessation of the training program. The assessments included 30-m sprint, vertical jump, 1-repetition-maximum (1RM) bench press, 1RM leg press, peak torque flexion and extension, anthropometric evaluation, and Rest-Q questionnaires.

After 5 wk of strength and power training, 30-m sprint time reduced in FOR (0.29 ± 0.11 s, P = .049) and SAL (0.35 ± 0.05 s, P = .040) groups compared with PLA (+0.01 ± 0.11 s). No significant change was found in other assessments of strength, mood, or skinfold thickness.

When strength and power training is combined with the inhalation of FOR or SAL over a 5-wk period, moderately trained individuals experience an improvement in 30-m sprint performance.

Original document


Research / Study
8 April 2019
Chester, Neil J.
Dickinson, John W.
Loosemore, Mike
Marcora, Sam
Merlini, Michele
Whyte, Gregory
United Kingdom
Other organisations
Liverpool John Moores University (LJMU)
University College London (UCL)
University of Kent
Doping classes
S3. Beta-2 Agonists
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Scientific article
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Pdf file
Date generated
27 March 2019
Date of last modification
24 April 2019
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