Detection of anabolic residues in misplaced implantation sites in cattle

Detection of anabolic residues in misplaced implantation sites in cattle / Andreas Daxenberger, Iris G. Lange, Karsten Meyer, Heinrich H.D. Meyer. - (Journal of AOAC International 83 (2000) 4 (July-August); p. 809-819). - PMID: 10995107


Eight weeks before slaughter, 26 heifers, 2 calves, and 1 steer were implanted with licensed anabolic preparations at off-label injection sites. After slaughter, 24 of 31 implantation sites (77%) were detected. Residual pellets of Revalor H contained a mean of 42.9 mg trenbolone acetate (range 19.8-57.7 mg) and 4.6 mg (1.96-6.45 mg) estradiol, corresponding to 30% (19.8-57.7%) and 32.7% (14.0-46.6%) of the originally applied dose, respectively. In the tissue areas containing residual Revalor H pellets, total residues ranged from 14.8 microg to 12.6 mg trenbolone acetate, 41.7 microg to 1.45 mg trenbolone, and 11.1 microg to 3.39 mg estradiol. The outer tissue areas of the injection sites contained <2 microg hormones. The preparations Synovex H, Finaplix H, Implus S, and Component EC behaved similarly to Revalor H. Residues of Synovex Plus were low, whereas the Compudose silicone rubber contained 58.8% of the implanted dose, but left no significant tissue residues. If implantation sites are processed in meat manufacturing, international threshold levels of the respective substances will be exceeded in tons of meat products.

Original document


Research / Study
19 November 1999
Daxenberger, Andreas
Lange, Iris, G.
Meyer, Heinrich H.D.
Meyer, Karsten
Other organisations
Technische Universität München (TUM) - Technical University of Munich
Doping classes
S1. Anabolic Agents
Trenbolone (17β-hydroxyestr-4,9,11-trien-3-one)
Meat contamination
Document category
Scientific article
Document type
Pdf file
Date generated
9 May 2019
Date of last modification
4 June 2020
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