Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids

Effective treatment and prevention of attempted suicide, anxiety, and aggressiveness with fluoxetine, despite proven use of androgenic anabolic steroids / Julio M.X. Amaral, Monica C. Padilha, Silvana V. Chagas, Julien S. Baker, Carrie Mullen, Leonardo Vieira Neto, Francisco R. Aquino Neto, Marcelo S. Cruz. - (Drug Testing and Analysis (2020) 17 August)

  • PMID: 32808487
  • DOI: 10.1002/dta.2912

Abstract

The treatment of a man who attempted suicide after experiencing symptoms of anxiety and aggressiveness associated with the use of androgenic-anabolic steroids (AAS) is described. This report includes 30 days of inpatient treatment and a 6-month follow-up. Regular use of fluoxetine apparently prevented the onset of anxiety, depression, aggressiveness, and suicide ideation, even with the concurrent use of AAS. The urinary concentration of androgens, metabolites of AAS, and fluoxetine were monitored through analysis of urinary samples by the Brazilian Laboratory of Doping Control. Our results are congruent with previous findings describing the risk of suicide prompted by AAS use as well as the efficacy of fluoxetine in the treatment of mood disorders associated with the use of anabolic steroids.

Original document

Parameters

Science
Case report
Date
17 August 2020
People
Amaral, Julio M.X.
Baker, Julien S.
Chagas, Silvana V.
Cruz, Marcello S.
Mullen, Carrie
Neto, Francisco R.
Neto, Leonardo Vieira
Padilha, Monica C.
Country
Brazil
Hong Kong
United Kingdom
Language
English
Other organisations
Hong Kong Baptist University (HKBU)
Instituto Brasileiro de Geografia e Estatística (IBGE) - Brazilian Institute of Geography and Statistics
King's College London (KCL)
Universidade Federal do Rio de Janeiro (UFRJ)- Federal University of Rio de Janeiro
University of the West of Scotland
Laboratories
Rio de Janeiro, Brazil: Laboratório Brasileiro de Controle de Dopagem – LBCD – LADETEC / IQ - UFRJ
Analytical aspects
Mass spectrometry analysis
Doping classes
S1. Anabolic Agents
Medical terms
Health effects
Document category
Scientific article
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Pdf file
Date generated
2 September 2020
Date of last modification
13 September 2020
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  • Legal Source
  • Education
  • Science
  • Statistics
  • History
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  • Country
  • Language
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  • ADRV
  • Legal Terms
  • Sport/IFs
  • Other organisations
  • Laboratories
  • Analytical aspects
  • Doping classes
  • Substances
  • Medical terms
  • Various
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