Anabolic steroids detected in bodybuilding dietary supplements - a significant risk to public health

Anabolic steroids detected in bodybuilding dietary supplements - a significant risk to public health / V. Abbate, A.T. Kicman, M. Evans-Brown, J. McVeigh, D.A. Cowan, C. Wilson, S.J. Coles, C.J. Walker. - (Drug Testing and Analysis 7 (2015) 7 (7 July); p. 609-618)

  • PMID: 25284752
  • DOI: 10.1002/dta.1728

Abstract

Twenty-four products suspected of containing anabolic steroids and sold in fitness equipment shops in the United Kingdom (UK) were analyzed for their qualitative and semi-quantitative content using full scan gas chromatography-mass spectrometry (GC-MS), accurate mass liquid chromatography-mass spectrometry (LC-MS), high pressure liquid chromatography with diode array detection (HPLC-DAD), UV-Vis, and nuclear magnetic resonance (NMR) spectroscopy. In addition, X-ray crystallography enabled the identification of one of the compounds, where reference standard was not available. Of the 24 products tested, 23 contained steroids including known anabolic agents; 16 of these contained steroids that were different to those indicated on the packaging and one product contained no steroid at all. Overall, 13 different steroids were identified; 12 of these are controlled in the UK under the Misuse of Drugs Act 1971. Several of the products contained steroids that may be considered to have considerable pharmacological activity, based on their chemical structures and the amounts present. This could unwittingly expose users to a significant risk to their health, which is of particular concern for naïve users.

Parameters

Science
Study
Date
7 July 2015
People
Abbate, V.
Coles, S.J.
Cowan, David A.
Evans-Brown, Michael
Kicman, A.T.
McVeigh, Jim
Walker, C.J.
Wilson, C.
Country
United Kingdom
Language
English
Other organisations
European Monitoring Centre for Drugs and Drug Addiction (EMCDDA)
King's College London (KCL)
Liverpool John Moores University (LJMU)
University of Southampton (Soton)
Laboratories
London, United Kingdom: Drug Control Centre
Analytical aspects
Mass spectrometry analysis
Medical terms
Health effects
Various
Contamination
Gym/fitness environment
Supplements
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Abstract
Date generated
7 September 2020
Date of last modification
13 September 2020
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  • Various
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