Recreational Use of Selective Androgen Receptor Modulators

Recreational Use of Selective Androgen Receptor Modulators / Melissa A. Burmeister, Timothy K. Fincher, William H. Graham. - (US Pharmacist 45 (2020) 60 (18 June); p. 15-18)


ABSTRACT:

Selective androgen receptor modulators (SARMs) are anabolic compounds that bind to androgen receptors. They have been studied as potential treatments for cancer, osteoporosis, sexual dysfunction, multiple sclerosis, Alzheimer’s disease, and muscle wasting. Recently, SARMs have been placed in various supplements marketed to fitness enthusiasts. SARMs have been found to reduce endogenous testosterone, affect cholesterol levels, and alter liver function. Recreational users of SARMs may take them in combination with each other on a cyclical basis. They may also practice postcycle therapy, which involves the use of SERMs in between cycles to help restore hormone balance. Pharmacists should be aware of the adverse side effects of SARMs use in order to advise individuals of the potential risks.

Original document

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Science
Review
Date
18 June 2020
People
Burmeister, Melissa A.
Fincher, Timothy K.
Graham, William H.
Country
United States of America
Language
English
Other organisations
Sanford Burnham Prebys Medical Discovery Institute (SBP)
William Carey University School of Pharmacy (WCUSOP)
Doping classes
S1. Anabolic Agents
Substances
Andarine
Enobosarm (ostarine)
LGD-4033 (ligandrol)
RAD140
Selective androgen receptor modulators (SARMs)
Various
Amateur / club / recreational sport
Gym/fitness environment
Supplements
Document category
Scientific article
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Pdf file
Date generated
28 September 2020
Date of last modification
1 October 2020
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  • ADRV
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  • Analytical aspects
  • Doping classes
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  • Various
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