Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue

Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue / Hyun Gil Goh, Yoo Jin Lee, Tae Hyung Kim. - (Korean Journal of Gastroenterology 76 (2020) 3 (25 September); p. 167-170)

  • PMID: 32969366
  • DOI: 10.4166/kjg.2020.76.3.167


Abstract

Hepatic disorders with prominent cholestasis can be caused by a range of conditions, and anabolic androgenic steroids have been considered a cause of protracted cholestasis. A 29-year-old man who had taken an anabolic androgenic steroid analogue for 2 months visited the hospital complaining of jaundice and indigestion. After stopping the medication, the hyperbilirubinemia tended to decrease, but a transiently elevated aminotransferase level was observed. The endogenous testosterone level also decreased initially but recovered soon after. The liver function profiles were normalized after 2 months of conservative management. This case emphasizes that close drug history taking, including anabolic steroids, is important for identifying the cause of unexplained persistent jaundice.

Keywords: Anabolic agents; Chemical and drug induced liver injury; Jaundice; Steroids; Substance abuse; oral.

Original document

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Science
Case report
Date
25 September 2020
People
Goh, Hyun Gil
Kim, Tae Hyung
Lee, Yoo Jin
Country
Korea, Republic of
Language
English
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Korea University College of Medicine
Doping classes
S1. Anabolic Agents
Substances
Selective androgen receptor modulators (SARMs)
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Health effects
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Scientific article
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Date generated
5 November 2020
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6 November 2020
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