Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue

Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue / Hyun Gil Goh, Yoo Jin Lee, Tae Hyung Kim. - (Korean Journal of Gastroenterology 76 (2020) 3 (25 September); p. 167-170)

  • PMID: 32969366
  • DOI: 10.4166/kjg.2020.76.3.167


Abstract

Hepatic disorders with prominent cholestasis can be caused by a range of conditions, and anabolic androgenic steroids have been considered a cause of protracted cholestasis. A 29-year-old man who had taken an anabolic androgenic steroid analogue for 2 months visited the hospital complaining of jaundice and indigestion. After stopping the medication, the hyperbilirubinemia tended to decrease, but a transiently elevated aminotransferase level was observed. The endogenous testosterone level also decreased initially but recovered soon after. The liver function profiles were normalized after 2 months of conservative management. This case emphasizes that close drug history taking, including anabolic steroids, is important for identifying the cause of unexplained persistent jaundice.

Keywords: Anabolic agents; Chemical and drug induced liver injury; Jaundice; Steroids; Substance abuse; oral.

Original document

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Science
Case report
Date
25 September 2020
People
Goh, Hyun Gil
Kim, Tae Hyung
Lee, Yoo Jin
Country
Korea, Republic of
Language
English
Other organisations
Korea University College of Medicine
Doping classes
S1. Anabolic Agents
Substances
Selective androgen receptor modulators (SARMs)
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Health effects
Kidney / liver disease
Document category
Scientific article
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Date generated
5 November 2020
Date of last modification
1 December 2021
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