Potential risk for developing severe COVID-19 disease among anabolic steroid users

Potential risk for developing severe COVID-19 disease among anabolic steroid users / Flavio Cadegiani, Erica M. Lin, Andy Goren, Carlos G. Wambier. - (BMJ Case Reports 14 (2021) 2 (26 February))

  • PMID: 33637513
  • PMCID: PMC7919571
  • DOI: 10.1136/bcr-2021-241572


Abstract

A severe case of COVID-19 was observed in an otherwise healthy 28-year-old man who had taken oxandrolone 40 mg/day as an anabolic steroid. The patient had been taking oxandrolone for enhanced bodybuilding 30 days prior to presenting to an outpatient clinic with COVID-19 symptoms. The patient reported that his symptoms have rapidly worsened over the course of 4 days prior to presenting at the clinic. As part of an experimental antiandrogen treatment for hyperandrogenic men suffering from COVID-19, he was administered a single 600 mg dose of the novel antiandrogen proxalutamide. Twenty-four hours after administration of this dose, marked improvement of symptoms and markers of disease severity were observed. To our knowledge, this is the first case that potentially links anabolic steroid use to COVID-19 disease severity.

Original document

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Science
Case report
Date
26 March 2021
People
Cadegiani, Flavio
Goren, Andy
Lin, Erica M.
Wambier, Carlos G.
Country
Brazil
United States of America
Language
English
Other organisations
Corpometria Institute, Brasilia
Universidade Federal de São Paulo (UNIFESP) - Federal University of São Paulo
Warren Alpert Medical School of Brown University
Doping classes
S1. Anabolic Agents
Substances
Oxandrolone
Medical terms
COVID-19
Health effects
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Scientific article
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Date generated
4 May 2021
Date of last modification
28 May 2021
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