Effect on sports drug tests of ingesting meat from steroid (methenolone)-treated livestock

Effect on sports drug tests of ingesting meat from steroid (methenolone)-treated livestock / A.T. Kicman, D.A. Cowan, L. Myhre, S. Nilsson, S. Tomten, H. Oftebro. - (Clincal Chemistry 40 (1994) 11 Pt 1 (November); p. 2084-2087) 

  • PMID: 7955383


Abstract

Anabolic-androgenic steroids are widely misused in human sports and are also used as growth promoters in livestock. Athletes who consume meat containing such hormone residues may risk failing a sports drug test. Prompted by an athlete's defence case, we questioned whether the consumption of small livestock given doses of anabolic steroid, orally or intramuscularly, could generate positive results in samples tested by our analytical procedures. We analyzed urine from eight men who consumed chickens that had been either fed with methenolone acetate (1 mg/day) from day 0 to 21 or injected with methenolone heptanoate depot (1 mg/intramuscular injection) on days 0, 7, and 14 and slaughtered on day 22. No methenolone or characteristic major metabolite was detected in samples from subjects who ate meat from the orally dosed chickens. However, 50% of the samples collected 24 h after consumption of the intramuscularly dosed chickens were confirmed positive. Hence, eating meat containing small amounts of injected hormone may constitute a serious liability to the athlete.

Parameters

Science
Research / Study
Date
1 November 1994
People
Cowan, David A.
Kicman, Andrew T.
Myhre, L.
Nilsson, S.
Oftebro, H.
Tomten, S.
Country
United Kingdom
Language
English
Laboratories
London, United Kingdom: Drug Control Centre
Analytical aspects
Testing method development
Doping classes
S1. Anabolic Agents
Substances
Metenolone
Various
Contamination
Food and/or drinks
Meat contamination
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Abstract
Date generated
7 June 2021
Date of last modification
3 March 2022
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