In this case involves respondent's first alleged anti-doping violation:
- assisted or incited others to use prohibited substances or prohibited technique thereby committing a doping offense in violation of the World Anti-Doping Agency Code or International Amateur Athletic Federation ("IAAF") rules and regulations
- traded, trafficked, distributed or sold prohibited substances in violation of the applicable WADA and IAAF rules and regulations
- engaged in covering up his rule violations during these proceedings thereby violating additional rules.

Respondent is related to BALCO/Victor Conte, evidence is provided. Respondent administered the drugs Modafinil and Repoxygen (EPO) to other Athletes. Modafinil especially to his wife Zhanna Block in out of competition periods.

Decision and award: respondent had committed a doping violation under each rules: Article 7.2 of IAAF rule 19 and violated IAAF Anti-Doping Rules 32.2(h), 56.3, and 56.4.
The sanction is a ten year period of ineligibility commencing January 1, 2009 and ending on January 1, 2019.
Respondent is prohibitted from participating in and having access to the training facilities of the USOC training Centers or other programs and activities of the USOC.

CoachTrue, WADA's computer-based learning tool, provides anti-doping education to elite and recreational level coaches. It is currently available in English, French and Spanish.

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The World Anti-Doping Agency's (WADA) mission is to lead a collaborative worldwide campaign for doping-free sport.

WADA was established in 1999 as an international independent agency composed and funded equally by the sport movement and governments of the world. Its key activities include scientific research, education, development of anti-doping capacities, and monitoring of the World Anti Doping Code (Code) – the document harmonizing anti-doping policies in all sports and all countries. WADA is a Swiss private law Foundation. Its seat is in Lausanne, Switzerland, and its headquarters are in Montreal, Canada.

WADA works towards a vision of a world where all athletes compete in a doping-free sporting environment.

TAS 2010/A/2201 Andrea Mangiante c/ CONI
CAS 2010/A/2201 Andrea Mangiante vs CONI

In December 2009 the Ufficio di Procura Antidoping del CONI(UPA), the Italian Anti-Doping Prosecutor's Office, has reported an anti-doping rule violations against the Athlete Andrea Mangiante after his samples - provided on 18 July 2008, 8 August 2008 and 25 March 2009 - showed a T/E ratio above the WADA threshold with GC-IRMS tested negative hereafter.
Other samples provided by the Athlete before, in between and after abovementioned data, in the period 2008 and 2009, showed normal t/e ratio results.

After notification the Athlete filed a statement in his defence, sustained by his experts, and was heard for the Italian National Anti-Doping Tribunal. The Athlete denied the use of prohibited substances and disputed the reliability of the samples.
Considering the arguments from the parties experts about the Athlete’s test results, the CONI TNA Panel decided on 10 July 2010 to impose a 2 year period of ineligibility on the Athlete.

Hereafter in August 2010 the Athlete appealed the CONI TNA decision with the Court of Arbitration for Sport (CAS).

The CAS Panel finds that the performed tests on the Athlete’s samples in 2008 and 2009 are valid and concludes that the Athlete failed to establish that there has been a violation of the IST.
In spite of the Athlete’s arguments, the Panel considers that the tests, conducted in compliance with international standards, showed that the Athlete has committed an anti-doping rule violation due to the presence of testosterone in his urine revealed exogenous administration of a prohibited substance.

Therefore the Court for Arbitration Panel decides on 14 March 2011:
1.) The appeal filed by Andrea Mangiante 28 July 2010 against the decision of the CONI National Anti-Doping Tribunal is dismissed.
2.) The decision of 5 July 2010 by the CONI National Anti-Doping Tribunal is confirmed.
3.) Andrea Mangiante is suspended for a period of two years, starting on 5 July 2010.

Detecting autologous blood transfusions: a comparison of three passport approaches and four blood markers / J. Mørkeberg, K. Sharpe, B. Belhage, R. Damsgaard, W. Schmidt, N. Prommer, C.J. Gore, M.J. Ashenden. - (Scandinavian journal of medicine & science in sports 21 (2011) 2 (April); p. 235-243)

• PMID: 19903320
• DOI: 10.1111/j.1600-0838.2009.01033.x

Abstract

Blood passport has been suggested as an indirect tool to detect various kinds of blood manipulations. Autologous blood transfusions are currently undetectable, and the objective of this study was to examine the sensitivities of different blood markers and blood passport approaches in order to determine the best approach to detect autologous blood transfusions. Twenty-nine subjects were transfused with either one (n=8) or three (n=21) bags of autologous blood. Hemoglobin concentration ([Hb]), percentage of reticulocytes (%ret) and hemoglobin mass (Hbmass) were measured 1 day before reinfusion and six times after reinfusion. The sensitivity and specificity of a novel marker, Hbmr (based on Hbmass and %ret), was evaluated together with [Hb], Hbmass and OFF-hr by different passport methods. Our novel Hbmr marker showed superior sensitivity in detecting the highest dosage of transfused blood, with OFF-hr showing equal or superior sensitivities at lower dosages. Hbmr and OFF-hr showed superior but equal sensitivities from 1 to 4 weeks after transfusion compared with [Hb] and Hbmass, with Hbmass being the only tenable prospect to detect acute transfusions. Because autologous blood transfusions can be an acute practice with blood withdrawal and reinfusion within a few days, Hbmass seems to be the only option for revealing this practice.

TAS 2010/A/2178 Pietro Caucchioli c. CONI & UCI

CAS 2010/A/2178 Pietro Caucchioli vs CONI & UCI

In June 2009 the UCI experts committee reviewed the data in the Athlete Biological Passport (ABP) of the Italian Athlete Pietro Caucchioli, based on the 13 blood samples collected between April 2008 and May 2009. The experts noted the Athlete’s hematological profile could only be explained by the use of a prohibited method.

As a result the UCI reported an anti-doping rule violation against the Athlete for the use of a prohibited method. Consequently on 3 June 2010 the Italian National Anti-Doping Tribunal (TNA) decided to impose a 2 year period of ineligibility on the Athlete.

Hereafter in July 2010 the Athlete appealed the TNA decision of 3 June 2010 with the Court of Arbitration for Sport (CAS). The Athlete disputed the ABP method, the independence of the experts committee and the reliability of the collected blood samples.

Follwing assessment the Panel determines that the ABP evidence is allowed and a reliable method for indirect detection of doping violations. The expert work independent for UCI and evaluate anonymized ABP samples.

The Panel deems that the Athlete failed to establish that there had been irregularities in the ABP method and concludes that he had committed an anti-doping rule violation through the use of a prohibited method (enhancement of oxygen transport).

Therefore the Court of Arbitration for Sport Panel decides on 8 March 2011 to uphold the TNA decision of 3 June 2010 and to impose a 2 year period of ineligibility on the Athlete, starting on 18 June 2009.

Drug Free Sport New Zealand (DFSNZ) has reported an anti-doping rule violation against the Respondent after his sample tested positive for the prohibited substances D-methamphetamine and D-Amphetamine. After the notification a provisional suspension was ordered. Respondent filed a statement in his defence and was heard for the Tribunal.

Respondent admitted the violation and he stated that it was the result of recreational drug use. He made submissions, through his representative, seeking a modification of the normal penalty in of his personal circumstances to that he could continue to actively participate in sport.

The Tribunal finds it has no discretion in a case such as this, where prohibited substances are involved and no defence available under the Rules had been established, other than to impose the mandatory penalty of two years.
Therefore the Sports Tribunal of New Zealand decides to impose a 2 year period of ineligibility on the Respondent starting on the date of the provisional suspension, i.e. on 18 November 2010.

Urinary excretion profiles of toremifene metabolites by liquid chromatography-mass spectrometry. Towards targeted analysis to relevant metabolites in doping control / Monica Mazzarino, Xavier de la Torre, Francesco Botrè

• Analytical and Bioanalytical Chemistry 401 (2011) 2 (August), p. 529–541
• PMID: 21380606
• DOI: 10.1007/s00216-011-4695-y

Abstract

In the present study, toremifene urinary excretion studies were evaluated in order to examine main metabolic reactions and to select target metabolites in doping control analysis. Urine samples from three female subjects were collected every 3 h for at least 15 days after the oral administration of a single dose of Fareston® (60 mg). The elemental compositions of the compounds detected were determined by liquid chromatography-mass spectrometry using a time-of-flight system with accurate mass measurement. More detailed structure elucidation was obtained by monitoring the presence or absence of structure-specific ions, using product ion scan and neutral loss acquisition modes, whereas the metabolites urinary profiles were evaluated in selected reaction monitoring acquisition mode. The results showed that the main routes of phase-I modifications involved carboxylation of the chlorinated side chain, N-demethylation and hydroxylation in different positions. Fifteen metabolites were found in all subjects studied, most of them were detected for more than 10 days in the free, glucuronide and sulphate fractions, with a maximum of excretion generally after 9-22 and 34-47 h from drug administration. These metabolites can be divided in two groups: metabolites with the characteristic chlorine isotope pattern and metabolites without the characteristic chlorine isotope pattern. The most abundant and long-term compounds were the carboxylated metabolites followed by the hydroxylated metabolites. Their product ions originating after collision-induced dissociation were observed to occur prevalently in the dimethylaminoethoxy and in the chlorinated side chains. These structure-specific ions were used to design screening and confirmation procedures to positively identify toremifene administration in doping control analysis.

Residuos de fármacos anabolizantes en carnes destinadas al consumo humano = Residues of anabolic drugs in meat intended for human consumption / Álvaro L. Fajardo-Zapata, Francy J. Méndez-Casallas, Luis H. Molina. - (Universitas Scientiarum 16 (2011) 1 (January/April); p. 77-91)

Resumen

La producción de carne para el consumo humano es uno de los renglones importantes dentro de la economía de un país, tiene una gran importancia socioeconómica ya que sirve como base para el desarrollo, generación de empleo y sostenibilidad. La demanda de proteína de origen animal es uno de los elementos más preciados y necesarios para mantener el adecuado desarrollo biológico de los seres humanos en crecimiento así como fuente de renovación de los tejidos. Este consumo ha aumentado porque las poblaciones y las migraciones hacia las ciudades crecen día tras día, lo cual genera que la oferta se torne insuficiente y se requiera acelerar, tecnificar y mejorar el proceso productivo de la carne. También se busca una disminución en los costos productivos por parte de los productores de este sector de la economía, lo que lleva a la utilización e incorporación de tecnología y de conocimientos de vanguardia con el fin de mejorar el rendimiento en la producción de carne; dentro de los nuevos conceptos se ha incorporado el conocimiento científico sobre crecimiento y desarrollo, trasladándolo al campo de la producción animal, lo que ha implicado el uso de hormonas y promotores del crecimiento (esteroides anabolizantes y otros), como fuentes para acelerar e incrementar la producción. Si bien es cierto, se ha logrado un incremento en la producción, los residuos de las sustancias usadas pueden quedar en la carne que se destina para el consumo humano y pueden generar alteraciones en el estado de salud de quienes la consumen.

Abstract

Residues of anabolic drugs in meat intended for human consumption. The production of meat for human consumption is one of the important items in the economy of a country. This activity has great socio economic importance as it serves as a basis for development, employment generation and sustainability of a country. The demand for animal protein is one of the most precious and necessary factors to maintain a proper biological development of human beings in active growth as well as being a source of growth and tissue regeneration. Consumption has increased because populations continue to grow and there is continuous migration to the cities, which makes the offer insufficient, and therefore it is necessary to accelerate, introduce technology and improve the meat production process. Industry also seeks a reduction in production costs by producers in this sector of the economy, leading to the use and incorporation of technology and cuttingedge knowledge to improve yield production of meat. Such knowledge comprises the scientific basis of the use of growth hormones and promoters (anabolic steroids and others) to accelerate and increase the production of meat. Although there has been an increase in production, residual substances can remain in the meat intended for human consumption which can lead to changes in the health of consumers.

In February 2011 the Agenţia Naţională Anti-Doping (ANAD), the National Anti-Doping Agency of Romania, has reported an anti-doping rule violation against the Athlete Vlad Dogaru after his sample tested positive for the prohibited substance methylhexaneamine (dimethylpentylamine).
At the hearing the Athlete stated he used the supplement Jack 3D. Laboratory analysis showed the presence of the prohibited substance methylhexaneamine (dimethylpentylamine) in the supplement.
The ANAD Hearing Commission decides to impose a 3 month period of ineligibility on the Athlete, starting on the date of the provisional suspension.

In order to provide athletes with basic information about their rights and responsibilities in the doping control process, WADA, in partnership with the Vancouver Organizing Committee for the 2010 Olympic and Paralympic Winter Games (VANOC), has developed a doping control video.

This 5-minute video is intended to provide a general overview of the doping control process while raising awareness of the athlete’s rights and responsibilities. The video outlines each of the phases of the doping control process:

Athlete selection
Athlete notification
Sample collection
Laboratory analysis
Results management

The video, currently available in nine languages (Arabic, Croatian, English, French, German, Greek, Portuguese, Russian, and Spanish), can be ordered by stakeholders at no cost for use as part of their information and education efforts. Those interested in producing a co-branded version of the video with their own logo or a version in their own language (voiceover or subtitles) can contact WADA at info@wada-ama.org.

The World Anti-Doping Agency's (WADA) mission is to lead a collaborative worldwide campaign for doping-free sport.

WADA was established in 1999 as an international independent agency composed and funded equally by the sport movement and governments of the world. Its key activities include scientific research, education, development of anti-doping capacities, and monitoring of the World Anti Doping Code (Code) – the document harmonizing anti-doping policies in all sports and all countries. WADA is a Swiss private law Foundation. Its seat is in Lausanne, Switzerland, and its headquarters are in Montreal, Canada.

WADA works towards a vision of a world where all athletes compete in a doping-free sporting environment.